In this article, we will consider the preparation "Eutiroks" (instruction, side effects and reviews).
This medication is synthetichormonal agent, analogous to the hormone, which is produced by the thyroid gland, that is, thyroxine. The active ingredient of the drug is levothyroxine sodium. In the human body, "Eutirox" affects the process of metabolism, and, in addition, on growth with the development of tissues. Apply the medicine in order to fill the deficiency of thyroid hormones. Further, we will consider in detail the instructions for "Eutirox".
Small doses of the drug act in such a way thataccelerate the synthesis of fats with proteins. Average doses of the drug can enhance the development and growth of tissues along with their need for oxygen. In addition, the drug enhances the metabolism (that is, proteins, carbohydrates and fats). In parallel, the work of the nervous, cardiac and vascular systems is stimulated. Large dosages of the drug contribute to the oppression of the endocrine glands, that is, the hypothalamus and pituitary gland. According to the instructions to "Eutirox", side effects are not limited to this.
The therapeutic effect, as a rule, comes aftertwelve days of taking the medicine. In the event that the patient has a lower thyroid hormone level, the effect of the drug comes much faster after five days of treatment. In the treatment of diffuse goiter, the therapeutic effect is noted only after a five-month course. From the human body, the products of the drug exchange are excreted along with the bile directly through the intestine, a certain proportion leaves with urine. At the end of treatment, the drug has its effect for another two weeks.
According to the instruction, "Eutirox" is produced intablets, which contain 25, 75, 125, as well as 150 micrograms of the main active ingredient of levothyroxine sodium. Tablets are packaged in twenty-five pieces in a blister pack. In one package is sold for fifty or a hundred tablets. Further we will consider, in what cases the medicinal preparation is appointed.
As the instruction informs, the preparation "Eutiroks" is appointed to patients in the following cases:
The drug "Eutiroks" according to the instructions has many different contraindications, we will consider them further.
With regard to the use of this drug, there are a number of the following contraindications:
As indicated by the instructions for use,"Eutiroks" should be used with caution in the presence of coronary heart disease, for example, it can not be taken in the case of the development of pathologies such as atherosclerosis, a previous myocardial infarction and angina. Also, it is not suitable for use in case of cardiac rhythm disturbance, development of hypertensive disease, diabetes mellitus and malabsorption syndrome (impaired absorption of nutrients).
Caution is recommended whenprolonged presence of severe hypothyroidism, and, in addition, in the absence of proper therapy in patients with insufficient adrenal function. The medicine for treatment and at use of thyreostatics - preparations which suppress function of a thyroid gland is not suitable. It should also be noted that in case of any disputable issues regarding the use of this drug, medical advice and careful dose adjustment is required. If the correct dosage is not observed, as well as in a number of other cases, various side effects may occur. Instructions for use, reviews of "Eutirox" this is confirmed.
In the presence of hypersensitivity tothe components of the drug presented are likely to manifest an allergic reaction. Other side effects of Eutirox, provided that the correct dosage is chosen, usually does not cause. In case of incorrect, for example, low dosage, hypothyroidism is likely to manifest, which will be manifested in decreased ability to work, sluggishness, puffiness of face and swelling, increase in body weight, constipation, memory loss and drowsiness. This is indicated in the instructions for use with Eutirox. Feedback on the side effects will be considered at the end of the article.
In the case of an overestimated dose of the drug,there are symptoms of thyrotoxicosis, which are expressed in the manifestation of pain in the heart, arrhythmia, palpitations, anxiety, sleep disturbance, trembling in the body, loss of appetite, diarrhea, vomiting, weight loss, excessive sweating, seizures and menstrual irregularities. If you experience this symptomatology during therapy, you should consult your doctor for a second consultation.
In accordance with the instructions to "Eutirox"The daily dose of the drug is taken on an empty stomach, for half an hour before breakfast. The tablet is swallowed whole and not chewed, but washed down with water. The daily dose is selected strictly individually, which depends on the immediate purpose of the appointment, and, in addition, on the nature of the disease, the concomitant diseases and the age of the patient. Patients with the development of euthyroid goiter are prescribed therapeutic daily doses from 75 to 200 micrograms. The prophylactic dose after the operation is also 75-200 micrograms per day.
Patients who suffer from thyrotoxicosis,daily dose of the drug is prescribed as a part of complex therapy individually from 50 to 100 micrograms. Duration of treatment course doctors choose in each case individually. After the operation associated with thyroid cancer, in order to prevent relapses, patients are assigned 50 to 300 micrograms of Eutirox per day. The dosage regimen for the test for thyroid suppression is as follows:
Considering that "Eutiroks" is absolutely identicalnatural thyroid hormone, with an overestimated dose of the drug, there are symptoms that are characteristic of thyrotoxicosis. Thus, the main signs of an overdose with this drug are various manifestations on the part of the heart and vessels, which will manifest itself in the increase in the pulse, the rhythm of the heart activity, and, in addition, some pain may occur. In addition to these side effects, reactions also occur in the form of decreased appetite, vomiting, diarrhea, loss of body weight, sleep disorders, menstrual cycle malfunction, tremors in the limbs, seizures, severe sweating and anxiety.
In case of symptoms of overdose, doctorcan reduce the daily dose of "Eutirox" or even cancel the drug for a certain period of time, which depends on the severity of side effects. Renewal therapy should begin at a lower dosage.
"Eutirox" is a drug that shouldbe used and canceled only as prescribed by the doctor. After discontinuation of therapy with the drug, its effect continues for another twelve days. Whether to cancel the drug at one time or gradually reduce the dose - only the doctor decides.
What else does the instruction for the use of "Eutirox" tell us?
It is also used in pediatrics intherapy of congenital hypothyroidism. Dosage is selected depending on the body weight and age of the child. Thus, the instruction for the use of the drug for children is as follows:
The tablet of the drug, before giving the baby, is dissolved in normal water until a fine suspension appears. Then the received medicine is given to the child for half an hour before feeding.
In the event that a woman received Eutirox beforepregnancy in order to treat hypothyroidism, then it is required to continue taking this medication during the gestation period, and, in addition, when the baby is breastfed. But the dose of "Eutirox" should be reviewed by a doctor. This is important, since during pregnancy, the level of globulin increases, which is one of the protein fractions of the blood plasma, it binds thyroxine.
The amount of a drug that falls into the breastmilk, is insignificant even in the case of receiving high doses of the drug, so the drug can not cause any disturbances in the baby's body.
This is confirmed by the instruction for use attached to Eutirox.
The initial daily dose in the presence of hypothyroidismfor women under the age of fifty-five years are 100 micrograms, and for men of the same age group, 150 micrograms. The dose is selected at a rate of 1.8 micrograms per kilogram of body weight. For patients after fifty-five with concomitant pathologies of the heart, the initial daily dose should be 25 micrograms.
In the presence of significant obesityCalculation of dosage is carried out on the so-called "ideal weight", that is, the normal body weight for concomitant growth. The initial dose is gradually increased by 25 micrograms per day at intervals of a couple of months to obtain a normal content of thyroid-stimulating hormone in the blood. In cases of negative dynamics on the part of the heart and vessels, correction of the therapy of cardiac pathology is required.
Against the backdrop of a heavy and prolonged currentHypothyroidism with an initial daily dose of 12.5 micrograms. Increase the dose, given the level of thyroid-stimulating hormone. The drug in the presence of hypothyroidism is usually taken throughout life.
The instruction on the application to "Eutirox" contains andother information. After surgical treatment for euthyroid goiter, this drug is usually administered in a daily dose of up to 200 micrograms in order to prevent recurrence of the disease. In cases of partial or complete removal of the thyroid gland, the daily dose will be up to 300 micrograms. In such situations, substitution therapy "Eutiroksom" is spent the whole life.
According to the instructions for use, "Eutirox" insmall dosages can speed up the synthesis of proteins. If you use it in medium doses, then the metabolism of carbohydrates with proteins and fats will be stimulated. This effect of the drug on the metabolism will certainly lead to an early reduction in body weight. True, it is worth noting that the instructions for the use of "Eutiroks" for weight loss is not recommended. Self-use of this medication for weight loss can lead to serious consequences. Therefore, it must be borne in mind that taking a hormonal drug that is not controlled by a doctor can certainly lead to disruptions in the work of various endocrine glands. This instruction warns. For weight loss, "Eutiroks" apply even dangerous.
The condition of prolonged hyperthyroidism leads toacceleration of metabolism, and, in addition, to an increase in appetite. In this situation, instead of the expected weight loss, you can, on the contrary, increase your body weight. At incorrect dosages, inevitable occurrence of a number of adverse reactions from the normal functioning of the nervous system. Also, the bone, heart and vascular system may suffer. "Eutiroks" like any other hormone drug should be used only on strict indications, and, in addition, under the supervision of a doctor. Therefore, it is undesirable to take it for weight loss purposes.
In accordance with the instructions for use of "Eutirox", you need to consider the following nuances of its interaction with other medicines:
This is confirmed by the instruction for use.
Synonyms are such drugs as"Levothyroxine" along with "thyroxine." Its structural analogues in terms of the active component are Bagotiroks, L-Tirok, Tiro-4, Novotiral and Tireotom. To drugs with a similar effect of exposure should be attributed "Thyreoidin".
Despite the fact that both of these drugs havethe same active substance - levothyroxine, each of them has its own peculiarities. The auxiliary components that make up their composition are different. There is a difference in the operation of the means. For example, the therapeutic effect of "thyroxine" is felt after five days, and "Eutirox" - after two weeks. With regard to curing for goiter or reducing its manifestations, such effects occur after a six-month course of treatment with both these drugs.
If Euthyrox is used correctlyhas any adverse reactions. "Thyroxine" in rare cases is capable of leading to side reactions in the form of increased appetite and weight gain. In more rare examples, it is possible to develop allergic dermatitis along with impaired kidney function and hair loss. Undesirable effects can occur even if there are minor changes in the dosing of "thyroxine."
In children with convulsive seizures, as well as in those,who suffers from epilepsy, against the background of the use of "thyroxine", there may be an additional deterioration in the condition. In cases of treatment with "Eutirox", no such deterioration was recorded.
Physicians, depending on the individual conditionpatients' health is selected and the drug, and dosage. In no case should you yourself change the medicine or the prescribed dosage, since such medicines have a powerful effect on the body with its hormonal background. Alternate use of medication is also not recommended, as this may distort the results of treatment.
We reviewed the instructions for use with Eutirox. I saw the side effects.
In some reviews of patients who tookEutiroks, you can find various comments about the appearance of side effects on the background of treatment with this medicine. In general, people call unwanted effects in the form of weight gain, hair loss and numbness of the limbs. But it should be noted immediately that such reactions from the body arise as a result of improperly selected dosages of the drug. Instructions for the use of side effects "Eutirox" describes in great detail.
There are also many positive reviewsabout the effectiveness of this medication. At the same time, people, on the contrary, report that they did not notice any side effects. In some reviews, there is a warning about self-abolition of this medication, as in this case serious consequences are possible. In this regard, it should be borne in mind that the appointment, along with the reception, exactly as the withdrawal of the drug, should be done only with the consent and under the supervision of the treating doctor.
In the article, instructions and references to "Eutirox" were presented.